In general, a diagnosis will be based on the presentation of important features (i.e., ‘blistering’ lesions) and a skin biopsy. A special immune test, known as direct immunofluorescence, is taken from a separate skin biopsy and is useful to confirm the diagnosis. Sometimes, the antibody titre count is also used to confirm the level of activity of the disease. The antibody titre count is a blood test that measures the level of the protein that is causing the condition. Once diagnosed, the patient can begin working with their healthcare professional to determine the best treatment plan for them.